Endocrine Abstracts

Background/Introduction: Lifestyle adaptations are crucial in the treatment of type 2 diabetes. However, implementation is difficult and patients especially with high glucose levels receive most often medication as first-line treatment instead of intensive lifestyle changes. We hypothesized that a primary lifestyle intervention as first-line treatment for newly diagnosed type 2 diabetes compared to standard of care is didactic, safe and can achieve metabolic control alone....

Background: Postprandial hypoglycemia is an increasingly recognized complication after bariatric surgery. Its hallmark is a pronounced glycemic rise after carbohydrate ingestion followed by an exaggerated hyperinsulinemic response. Recent studies have shown that IL-1β contributes to postprandial stimulation of insulin. Furthermore, inhibition of SGLT2 reduces excessive plasma glucose increase. Therefore, we investigated whether inhibition of IL-1β with the IL-1 recep...